The invention relates to a universal clamp for a strain tower lead terminal with a turning pulley for a 500-KV line. The clamp comprises an upper clamp part, a lower clamp part, and a trunnion hanging plate assembly connecting the upper clamp part and the lower clamp part. A first clamp groove is formed in a rear end portion of the upper clamp part by corresponding to an upper end of a lead terminal yoke plate; a second clamp groove is formed in a rear end portion of the lower clamp part by corresponding to the lower end of the lead terminal yoke plate; and locking bolts are arranged in the opening of the first clamp groove and the opening of the second clamp groove respectively. An opening hole for lead screw or pull rod connection is formed in the trunnion hanging plate assembly. When the universal clamp is used for replacing an insulator or an insulator chain, any influence from a yoke plate type, a channel steel specification, a bolt pitch, a pitch or a grading ring can be eliminated; the universality is high; tool assembling can be carried out without the need to dismount the grading ring; and working and equipment safety can be guaranteed.