The invention discloses an inclined wedge mechanism with a lateral material pressing function. The inclined wedge mechanism with the lateral material pressing function comprises an upper die seat, an inclined wedge body and a lower die seat, wherein the bottom of the upper die seat is provided with a nitrogen spring; a safety hook and a safety bolt penetrate through a through hole in the upper die seat, and then are fixedly connected with inclined wedge body; the inclined wedge body is provided with a material pressing core, a punching head upper die and a trimming knife; the material pressing core cooperates, in a sliding manner, with a guide post mounted on the inclined wedge body; the top of the lower die seat is provided with a driving block and a lower die; the driving block cooperates with the inclined wedge body in the sliding manner; and the lower die cooperates with the punching head upper die and the trimming knife. By using the inclined wedge mechanism with the lateral material pressing function, a material pressing problem that a position cannot be corrected and punched forwards can be solved; and a sheet metal component is prevented from generating profile change due to trimming and hole punching, so as to improve the welding and assembly precision of a whole car.