The invention provides a Zr-Sn-Nb-Hf alloy bar. The Zr-Sn-Nb-Hf alloy bar comprises the following components in percentage by mass: 0.8%-1.2% of Sn, 0.2%-0.4% of Nb, 0.8%-1.6% of Hf and the balance of Zr and inevitable impurities. The invention further provides a method for manufacturing the Zr-Sn-Nb-Hf alloy bar. The method comprises the following steps: 1, a Sn-Nb-Hf intermediate alloy is manufactured through vacuum non-consumable arc melting; 2, the Sn-Nb-Hf intermediate alloy is broken and is uniformly mixed with sponge Zr, and then the mixture is compacted into an electrode; 3, an ingot casting is obtained through vacuum consumable arc melting; 4, a semi-product bar blank is obtained through hot extrusion; and 5, the Zr-Sn-Nb-Hf alloy bar is obtained through hot extrusion. The Zr-Sn-Nb-Hf alloy bar has excellent room-temperature and high-temperature strength and good plasticity, and can be used as a structure material under a next-generation high-burnup condition.