The invention relates to roof panel systems, and provides a roof panel system capable of improving the wind uplift resistance. The roof panel system comprises a plurality of purlines and a plurality of roof panels. The various roof panels are fixedly mounted on the corresponding purlines, each roof panel comprises a bottom panel and two connecting portions, each end of each bottom panel extends in a bent manner to form the corresponding connecting portion, every two adjacent roof panels are fixedly connected with each other by the two corresponding adjacent connecting portions, a locking device for being connected with another member is arranged at each connecting portion, the ends, which are far away from the bottom panels, of the connecting portions extend into the locking devices corresponding to the connecting portions and are compressed along the directions perpendicular to the bottom panels, and the various locking devices are mounted on the corresponding purlines. The roof panel system has the advantages that every two corresponding adjacent roof panels are fixedly connected with each other by the single corresponding locking device and are fixedly mounted on the corresponding purline, the roof panels and the corresponding locking devices are fixed by means of being compressed along the directions perpendicular to the bottom panels, and accordingly the roof panel system is high in wind uplift resistance.