The invention discloses a non-invasive ocular pressure detection sensor based on a micro-fluidic technology. The detection sensor comprises a corneal contact lens, a spiral inductor, a fringing capacitor and an inner ring capacitor, wherein cavities and a micro-fluidic channel are arranged in the corneal contact lens; the cavities and the micro-fluidic channel communicate and are used for keeping fluid, and the fluid is conveyed into the micro-fluidic channel; the amount of the fluid which is conveyed into the micro-fluidic channel is affected by ocular pressure , and capacitance of the inner ring capacitor varies with the amount of the fluid which is conveyed into the micro-fluidic channel; and a CLC loop is constituted by the fringing capacitor, the spiral inductor and the inner ring capacitor, so that the ocular pressure is detected. With the application of the ocular pressure detection sensor disclosed by the invention, the problem that the ocular pressure sensor is inconvenient for night supervision is effectively solved, and the fluctuation of the ocular pressure can be measured with high precision in a whole course within 24h; and the detection sensor has the advantages of being simple in structure, convenient to manufacture, high in sensitivity and broad in dynamic scope.