The invention relates to a method for leaching antimony from copper anode slime high-arsenic purified antimony slag. The method comprises the steps that the high-arsenic purified antimony slag with the granularity smaller than 2 mm is subjected to ore grinding and then is pretreated after ore grinding; sodium hydroxide and potassium permanganate are added; the leaching temperature and time, the liquid-solid ratio and the stirring speed are controlled; solid-liquid separation is conducted after reaction is over to obtain a pretreatment solution rich in arsenic and pretreatment slag; then sodium hydroxide and sodium sulphide are added into the pretreatment slag; the leaching temperature and time, the liquid-solid ratio and the stirring speed are controlled; and solid-liquid separation is conducted after reaction is over to obtain a leaching solution rich in antimony and leaching slag. The method has the advantages that the antimony leaching rate is high, the arsenic content of the antimony leaching solution is low, the process is simple, and the treatment cost is low.