The invention relates to a production method for super-hydrophobic superfine fiber synthetic leather. The production method comprises the following steps: enabling superfine fiber synthetic leather base cloth to pass through a first three-edition printer, respectively transferring an organic silicon pre-polymer dispersing solution onto the two surfaces of the superfine fiber synthetic leather base cloth under the transferring function of a printing roll on a first printing position and a second printing position, fully permeating the organic silicon pre-polymer dispersing solution on a third printing position, and then drying; and enabling the base cloth to pass through a second three-edition printer, respectively transferring a chain extender onto the two surfaces of the superfine fiber synthetic leather base cloth under the transferring function of the printing roll on the first printing position and the second printing position, fully permeating the chain extender on the third printing position, and then drying. The superfine fiber synthetic leather base cloth treated according to the method is characterized in that the contact angle of water on the surface is above 153 degrees, and the base cloth is not water-permeating within 24 hours under static conditions and has excellent anti-staining capacity. The super-hydrophobic superfine fiber synthetic leather produced according to the method can be used for producing shoes, sofa and outdoor articles for use.