The invention discloses a deflagration fracturing experiment device for a screen pipe. The device comprises a cement target, a casing pipe, a filling layer, the screen pipe, an inner pipe and a gunpowder column, wherein a lower-end cap is arranged at the bottom of the casing pipe; an upper-end cap with a center hole is arranged at the top of the casing pipe; a perforation hole simulation tube is perpendicularly arranged on the outer wall of the casing pipe, one end of the perforation hole simulation tube communicates with the inside of the casing pipe, and the other end is sealed; through holes are uniformly formed in the side wall of the inner pipe; the gunpowder column is connected with an electric detonator; the electric detonator is connected with an igniter arranged on the outside of the cement target through an ignition wire. The deflagration fracturing experiment device is used for evaluating damage of the deflagration fracturing process to the screen pipe, makes up the research blank in the field and provides a scientific basis for application of the deflagration fracturing technique in the screen pipe completion field.