The invention provides a waterproof alarm system for high and low voltage power equipment. The system comprises a 220V alternating current power supply, a rectifier device, a measurement and control device, a network switch, a remote communication device and a dispatching end master station system connected in sequence, wherein the measurement and control device is connected with a conductive device and an audible and visual alarm respectively. The waterproof alarm system for high and low voltage power equipment can prevent leakage liquid from dropping to the high and low voltage equipment to cause accidents, and can also timely feed the leakage of facilities above the high and low voltage power equipment back to a dispatching end, so that workers can timely maintain leakage points.