The invention relates to a linkage control device for a spraying machine with a dedusting fan and a purifying water curtain. When a purifying water curtain is blocked, an existing linkage control device for a spraying machine and a dedusting fan cannot stop spraying operation in time so that dust rises from all directions which affects the health of workers. Therefore, the linkage control device for a spraying machine with a dedusting fan and a purifying water curtain comprises an air supply pipeline, a water supply pipeline, a spraying machine, a dedusting fan, a water curtain nozzle and a PLC controller; branch pipes between magnetic valves and the water supply pipeline are provided with filters; an elastic corrugated hose is installed between the water curtain nozzle and the magnetic valves; the elastic corrugated hose comprises flanges installed at two ends and a corrugated hose between the two flanges; two sides under the water curtain nozzle are provided with an infrared emitter and an infrared receiver which form an infrared proximity switch; the infrared proximity switch is connected with the PLC controller. The invention has scientific design; when water supply is interrupted, spray operation can be timely stopped; the linkage control device is widely applied in various mines.