The invention discloses a joint power control and proportional fair scheduling method for D2D communication in a cellular network, relates to the field of D2D communication in the cellular network, and aims to solve the problem of common-channel interference between users and the problem of fairness between the users due to the fact that the maximum throughput capacity of a system is used as a target in the existing interference suppression algorithm. An optimal power control method is used for realizing interference suppression. Meanwhile, aiming at the problem of user fairness caused by the time-varying characteristic of a channel under the condition of coexistence of multiple users, the invention adopts the proportional fair scheduling method so as to meet the demand of the users for the fairness. A cellular network model for multiplexing uplink resources for D2D communication is constructed, and mathematical modeling and solving for joint power control and proportional fair scheduling are carried out for the network model. The interference suppression method for joint power control and proportional fair scheduling, which is provided by the invention, can guarantee the quality of user communication and improve the throughput capacity and the fairness of the system.