The invention relates to the field of intelligent furniture, in particular to a health-care mattress adopting cloud data interaction and an operating method of the health-care mattress. The health-care mattress comprises a data processing element and a functional element, wherein the data processing element comprises a control chip, pressure sensors, an audio collector, a temperature meter and an interaction device; a networking module, an analyzing and processing module and a control module are arranged on the control chip; the functional element comprises a top cushion, a bottom cushion, a temperature control cushion and a moving magnetic group, the temperature control cushion and the moving magnetic group are arranged between the bottom cushion and the top cushion, and a touch screen is arranged on the top cushion; support bars are arranged on the mattress, pressure sensors are arranged in the support bars, and the support bars comprise lifting bars and fixing bars; the temperature control cushion comprises temperature control tubes, airflow tubes, exhaust fans, a retaining frame and air blowers; the audio collector is arranged in the top cushion, a plurality of the pressure sensors are arranged in the support bars, the temperature meter is arranged on the lower surface of the top cushion, and the interaction device is connected with the touch screen.