The invention relates to the field of plant antibacterial technologies, in particular to a plant-derived antibacterial agent and liquid soap and toothpaste with the plant-derived antibacterial agent. The plant-derived antibacterial agent comprises traditional Chinese medicine extract including, by weight, 30%-90% of pericarpium granati extract, 5%-30% of radix et rhizoma rhei extract, 5%-20% of radix sophorae flavescentis extract, 1%-10% of radix paeoniae alba extract, 1%-10% of olea europaeal extract and 0.01%-5% of propolis extract. The plant-derived antibacterial agent, the liquid soap and the toothpaste have the advantages that gram-positive bacteria, gram-negative bacteria, saccharomyces and anaerobic bacteria can be inhibited by the plant-derived antibacterial agent, the plant-derived antibacterial agent is wide in antibacterial spectrum and can be applied to the toothpaste and the liquid soap, excellent antiseptic effects can be realized, usage of chemically synthesized antiseptics can be reduced, accordingly, irritation of products can be reduced, and the safety of the products can be improved.