The invention discloses a synthesis method of a dibenzofuran coupling compound. The dibenzofuran coupling compound is synthesized in one step by taking simple arene ether as a starting raw material, palladium acetate or palladium trifluoroacetate as a catalyst and oxygen as an oxidant in an organic solvent. By adopting the method disclosed by the invention, aryl is directly oxidized for coupling through C-H bond activation; compared with a traditional method, the operation is simple; an applicable range of substrates is wider and the reaction efficiency is higher; the synthesis method is environment-friendly, high in yield and high in atom utilization rate.