The invention discloses a medical surgery simulation system based on VR technology and transient noise removal technology The medical surgery simulation system includes a database storage unit, which stores model element information of a plurality of medical devices, performance information corresponding to the medical devices, and surgery type information relating to the medical devices; a scene building unit, which retrieves data information in the database storage unit in a virtual environment area for image and video editing of all the operation processes corresponding to each medical surgery; and a virtual reality imaging unit. According to the invention, medical personnel can have somatosensory experience of the performance and function of the medical devices while experiencing virtual reality technology and get a better exercise and knowledge of the medical technology in the medical surgery process, thereby achieving a more realistic understanding of the effect of the medical devices while having a good exercise and knowledge of a variety of medical surgeries.