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发明授权
CN106727797B 一种提取刺五加的方法 有权

一种提取刺五加的方法
摘要：
本发明涉及一种提取刺五加的方法，该方法包括以下步骤：1)粉碎；2)酶解；3)超声波提取；4)过滤；5)醇沉；6)大孔树脂吸附；7)非极性树脂吸附；8)色谱柱分离；9)灭菌超滤。该工艺使得刺五加的提取效率更高，还能够显著减少刺五加提取物中的极性和非极性杂质，并且减少病人因注射该刺五加提取物制成的刺五加注射液引起的皮疹、瘙痒、头晕、头痛和心悸等症状，提高注射药物的安全性。
摘要（英）：

The invention relates to a method for extracting radix acanthopanacis semticosi. The method comprises the following steps: 1) smashing; 2) carrying out enzymolysis; 3) carrying out ultrasonic extraction; 4) filtering; 5) carrying out alcohol precipitation; 6) carrying out macroporous resin adsorption; 7) carrying out nonpolar resin adsorption; 8) carrying out chromatographic column separation; 9) carrying out sterilization ultrafiltration. According to the technology, the extraction efficiency of the radix acanthopanacis semticosi is higher, the polar and nonpolar impurities in the radix acanthopanacis semticosi extract can be obviously reduced, in addition, symptoms, including rash, pruritus, dizziness, headache, palpitation and the like, caused by that radix acanthopanacis semticosi injection prepared from the radix acanthopanacis semticosi extract is injected into a patient can be reduced, and the safety of medicine injection is improved.

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