The invention relates to a five-wire system turnout driving system based on a double 2-vote-2 framework. The five-wire system turnout driving system comprises an interlocking lower computer IPS, an interlocking maintenance station SDM, a five-wire system turnout driver module PDDM5 and an all-electronic communication module EIOCOM2, wherein the five-wire system turnout driver module PDDM5, the all-electronic communication module EIOCOM2 and the interlocking lower computer IPS are sequentially connected with one another; the all-electronic communication module EIOCOM2 is connected with the interlocking maintenance station SDM; and the five-wire system turnout driver module PDDM5 acquires a turnout drive order through the interlocking lower computer IPS, controls a permissible relay and a directional relay in the five-wire system turnout to suck up and drop down, drives the turnout to rotate towards a specified direction and acquires representation information of the turnout after the turnout rotates in place. Compared with the prior art, the five-wire system turnout driving system disclosed by the invention has the advantages that the previous relay circuit is replaced by utilizing a high-performance circuit board, the construction and maintenance cost can be greatly reduced, and the like.