A data pipeline is used as a fundamental processing element for implementing techniques that automatically or autonomously perform signal processing-based learning in a process plant or monitoring system. Each data pipeline includes a set of communicatively interconnected data processing blocks that perform processing on one or more sources of data in a predetermined order to, for example, clean the data, filter the data, select data for further processing, perform supervised or unsupervised learning on the data, etc. The individual processing blocks or modules within a data pipeline may be stored and executed at different devices in a plant network to perform distributed data processing. Moreover, each data pipeline can be integrated into one or more higher level analytic modules that perform higher level analytics, such as quality prediction, fault detection, etc. on the processed data. The use of data pipelines within a plant network enables data collected within a plant control or monitoring system to be processed automatically and used in various higher level analytic modules within the plant during ongoing operation of the plant.