The invention discloses a nuclear-power-plant real-time information monitoring system frame detection and automatic configuration system and a method thereof. The system comprises a frame format distinguishing module, a graphic element database establishing module, a picture format detection module, a configuration format detection module, a configuration rule establishing module, a customized tool generation module and a configuration frame generation module. The method comprises a frame format distinguishing step, a graphic element database establishing step, a picture format detection step, a configuration format detection step, a configuration rule establishing step, a customized tool generation step and a configuration frame generation step. The system and the method have advantages that a rapid and convenient automatic frame configuration function is provided for a nuclear-power-plant real-time information monitoring system; frame upgrading time of the nuclear-power-plant real-time information monitoring system is greatly shortened; and a nuclear-power-plant real-time information monitoring system user can timely and visually know the newest operation state of each system of a nuclear power plant.