The embodiment of the invention provides a vehicle running control method and system. A plurality of vehicles comprise at least one main control vehicle and at least one controlled vehicle; vehicle-mounted terminals are respectively mounted on the main control vehicle and the controlled vehicle; and on the basis of the vehicle-mounted terminals, the main control vehicle and the controlled vehicle form a communication network. The vehicle running control method comprises the steps of setting vehicle data, wherein the vehicle data comprise a set vehicle distance and a set vehicle speed; transmitting the set vehicle distance and the set vehicle speed to the controlled vehicle; and enabling the controlled vehicle to adjust the distance from the main control vehicle according to the set vehicle distance and automatically run according to the set vehicle speed. According to the vehicle running control method and system, the controlled vehicle can achieve an automatic running purpose without operation and control of a driver.