The invention discloses a method for recovering valuable metals by comprehensively treating high-iron and low-germanium zinc oxide calcine and zinc sulfite. The method comprises the following steps: 1) primary leaching of zinc oxide calcine; 2) secondary leaching of zinc oxide calcine; 3) zinc sulfite analysis and ferric reduction; and 4) tannin germanium precipitation. In the process of recovering valuable metals by comprehensive treatment, the zinc sulfite analysis and the reduction of ferric ions, namely ferric sulfate in a solution into ferrous ions, namely ferrous sulfate are completed at one step by using a simple and convenient method, so that resources are sufficiently recycled, and the production cost is reduced; and the problems that zinc and germanium are recovered by analyzing zinc sulfite into a zinc sulfate solution and the ferric ions in a system for recovering zinc and germanium from the zinc oxide calcine cannot form an open path because of being enriched are simultaneously solved, meanwhile, the filtering performance for liquid-solid separation of the whole production system is also improved to ensure that the solution is clear and has no suspended matters, and consumption of tannic acid can be reduced and the grade of a germanium concentrate can be improved in the tannin germanium precipitation process.