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发明公开
CN106943339A 七叶皂苷A脂质体凝胶及其制备方法 无效 - 驳回

七叶皂苷A脂质体凝胶及其制备方法
摘要：
本发明公开了一种七叶皂苷A脂质体凝胶，它由七叶皂苷A、大豆磷脂、胆固醇、卡波姆、三乙醇胺、EDTA·2Na、薄荷脑等成分组成。本发明还公开了制备方法，包括制备脂质体和制备脂质体凝胶两个步骤。与普通凝胶剂相比，本发明公开的脂质体凝胶不仅具有更好的透皮吸收效果，而且具有缓控释作用，能够以一定速率缓慢释放，从而在皮肤内形成恒定的血药浓度，有利于延长药物的治疗时间，本发明还能减少皮肤刺激反应的发生率。
摘要（英）：

Aescin A liposome gel is disclosed. The aescin A liposome gel includes aescin A, soybean phospholipid, cholesterol, carbomer, triethanolamine, EDTA.2Na, menthol, and the like. A preparing method of the aescin A liposome gel is also disclosed and includes a first step of preparing liposome and a second step of preparing the liposome gel. Compared with common gel agents, the liposome gel has better transdermal absorption effects, has a controlled release function, and can be slowly released at a certain speed, thus forming a constant plasma concentration of a medicine in skin and prolonging the treatment time of a medicine. The aescin A liposome gel also can reduce the occurrence rate of skin irritative reactions.

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