The invention relates to a compound hibiseu manihot and wheat flour and a preparation method thereof. The compound hibiseu manihot and wheat flour is prepared from, by weight, 87-93% of wheat flour, 5-9 % of hibiseu manihot seed powder and 2-4% of hibiseu manihot stem and root powder. The preparation method comprises the steps that hibiseu manihot shells, hibiseu manihot stems and hibiseu manihot roots are cleaned and dried, the hibiseu manihot shells are threshed, the hibiseu manihot stems and the hibiseu manihot roots are sliced and smashed, the seeds are dried and smashed to obtain the hibiseu manihot stem and root powder and hibiseu manihot seed powder respectively; the wheat flour and the hibiseu manihot seed powder and the hibiseu manihot stem and root powder are put in a container for mixing, and the compound hibiseu manihot and wheat flour is obtained. The characteristic that the hibiseu manihot contains rich protein, flavone, dietary fiber, vitamins and the like is utilized, the shortcomings of poor protein quality and nutritional quality of traditional wheat flour are overcome, and the physiologically active ingredients in the flour are supplemented, so that the flour has the health-care functions of improving cardiovascular and cerebrovascular diseases, gastrointestinal diseases and human body immunity.