The invention discloses a procyanidine-enriched wine. The wine comprises grape pulp, grape seed extractive with procyanidine content not less than 98%, cane sugar, and zymosan. The invention further discloses a production method of the procyanidine-enriched wine. The method includes steps of peeling fresh grape and removing grape seeds, mashing the obtained grape pulp to obtain the grape syrup; taking the grape seeds as a raw material, and extracting the grape seed extractive from the grape seed; adding the grape seed extractive, the cane sugar, and zymosan in the grape syrup obtained after mashing the grape pulp, and fermenting the raw materials for at least 5 days continuously; after completing the fermentation, separating the wine from the material residue; moving the separated wine to a storage tank to mature. The procyanidine-enriched wine has the advantages of improving the procyanidine content in the wine, strengthening the health-care effect of the wine, removing the bitterness of the grape seeds and fermenting taste during the fermentation process, and greatly improving the wine taste.