The invention relates to an assistant analysis and diagnosis system based on an information system comprehensive network management system. The assistant analysis and diagnosis system comprises a data collection module, a data channel module, a data processing module, an application service module and a uniform display module. The data collection module is used for collecting data information of the system and other service systems, middleware, hosts and databases. The data channel module comprises pipeline and interfaces for internal and external data transmission through adoption of message middleware Active MQ and is used for providing cooperative service for internal and external interfaces of the system. The data processing module is used for normalizing collected data through adoption of an Esper event rule engine, storing real-time monitoring service, operation and performance data through adoption of a MongoDB data cache server and storing history data through adoption of an Oracle database. According to the application service layer module, an application server middleware is Tomcat and J2EE common software architecture is used for carrying out service logic and function development. The uniform display module is used for carrying out display by taking Ext as a foundation framework and displaying a process module and an icon through adoption of a Flex graphical assembly.