The invention provides a positioning mechanism and a van vehicle having same; the positioning mechanism comprises the following units: a first positioning block fixed in an interference mode and having a conical structure for positioning; a second positioning block fixed in a welding mode and having a positioning cavity, wherein the positioning cavity is used for containing the conical structure and matched in shape with the conical structure. When the positioning mechanism positions, the conical structure inserts into and abuts against the positioning cavity according to a positioning direction; the conical structure and the positioning cavity are concentrically arranged. The positioning mechanism is easy to install and good in reliability, can accurately position the van body and the frame, thus allowing said two to easily connect.