A method, a system and a computer-readable medium for detecting a wheel tread depth include a first detector, a second detector and a processor. The first detector is configured to detect a moving distance of a vehicle moved by at least one wheel. The second detector is configured to detect a number of tunes of the wheel while the vehicle moves the moving distance. The processor is electrically connected to the first detector and the second detector. The processor is configured to compute a current diameter of the wheel according to the moving distance and the number of tunes of the wheel and determine a parameter of the tread pattern of the wheel according to the current diameter of the wheel and a reference value.