The invention provides a satellite instruction sequence generation method based on a flexible weighted directed graph model. The detailed process comprises the specific steps of converting a satellite task instruction sequence into the flexible weighted directed graph model formed by nodes and a constraint relation thereof, wherein an edge in which the weight value is variable in the directed graph model is a flexible edge, and the weight value of the flexible edge is a flexible range; aiming at each node, according to an execution range of a front driving node of each node and the flexible range between the front driving node and a rear driving node, calculating an execution range corresponding to the flexible range; aiming at each node, according to the final execution time of the rear driving node of each node, the flexible range between the front driving node and the rear driving node and the execution range corresponding to the flexible range, calculating and renewing the execution range corresponding to each node, and determining the final execution time within the renewed execution range; then executing a corresponding instruction according to the final execution time corresponding to each node. In the satellite instruction sequence generation method based on the flexible weighted directed graph model, through all instruction execution moments determined by the method, a rigid instruction execution time interval requirement can be satisfied.