The invention provides a container truck automatic driving system and method. The system comprises a remote monitoring device which is used for generating a transportation task and a transportation route through a preset container transportation plan and the map of the port where a container is located, and a vehicle-mounted automatic driving device which is arranged on a container truck, and is used for receiving the transportation task and route issued by the remote monitoring device and controlling the container truck to travel based on the transportation route to complete the transportation task. According to the invention, the port ground and other infrastructure are free of large-scale transformation; and the problems of low transport efficiency and poor job reliability due to manual container truck driving are solved.