The invention discloses an active power distribution network double-layer planning method considering demand side response uncertainty. The content includes building a time sequence model of a wind turbine generator and a photovoltaic cell with consideration given to uncertainty of a wind power generation and photovoltaic power generation; building a time sequence model of a load with consideration given to randomness of power utilization of the load; making an analysis of demand side response uncertainty of a direct load control type, and building a cost function; building an upper layer planning model of active power distribution network double-layer planning considering the demand side response uncertainty, and adopting a differential evolution algorithm to solve the upper layer planning model; and building a lower layer planning model of the active power distribution network double-layer planning considering the demand side response uncertainty and adopting a non-dominated sorting genetic algorithm to solve the lower layer planning model. The active power distribution network double-layer planning method performs planning of an active power distribution network, can effectively reduce the comprehensive cost of the power distribution network, better meets the running characteristic of the active power distribution network, and is high in practicability.