The invention provides a manufacturing method of a high-intensity bolt hole-group truss. The manufacturing method comprises the steps of providing an upper chord member and a lower chord member, and positioning the upper cord member and the lower chord member which are oppositely arranged on a splicing platform, wherein the upper chord member and the lower chord member comprise multiple subsidiary chord members, and a cutting gap is reserved between connectors of two adjacent chord members; providing tool connecting plates, positioning the tool connecting plates on the connectors of the two adjacent chord members, and fixing the tool connecting plates to the connector of the two adjacent chord members through spot welding; dismantling the upper chord member and the lower chord member from the splicing platform, and cutting off the tool connecting plates along the cutting gaps through a cutting device; manufacturing screw holes in the screw hole positions corresponding to the tool connecting plates; dismantling the tool connecting plates on the subsidiary cord members after hole manufacturing is completed. The manufacturing method of the high-intensity bolt hole-group truss can effectively guarantee the screw hole precision of the subsidiary chord members, so that the screw holes of the subsidiary chord members are consistent with those of the product connecting plates, and the hole penetrating rate of the high-intensity bolt is increased. The invention further relates to the high-intensity bolt hole-group truss.