The invention discloses a grouting construction sealing method for a semi-flexible anti-rutting pavement. The method comprises the following steps of cleaning the periphery of a pavement grouting area by adopting a blowing and drying device or manpower before grouting construction; pasting road edge stones and asphalt pavement adjacent to the periphery of the grouting area by adopting a double-faced adhesive tape and lightly tearing off double-faced adhesive tape isolation paper after pressing the double-faced adhesive tape; and pasting a light foaming strip in the middle of the double-faced adhesive tape, covering the foaming strip with a thin film and pressing and pasting two sides of the thin film on the bottom double-faced adhesive tape. According to the grouting construction sealing method for the semi-flexible anti-rutting pavement, slurry can be prevented from polluting adjacent pavement and road edge stones during grouting construction of the semi-flexible anti-rutting pavement, the grouting efficiency and the grouting plumpness can also be improved, and the engineering quality of the semi-flexible pavement is greatly improved.