The invention discloses 2-amido ethanesulfonamide compounds. The compounds have structures shown as a general formula (1) or a general formula (2), wherein R is any one selected from C1-C8 substituted or unsubstituted alkyl, substituted or unsubstituted furyl, substituted or unsubstituted pyridyl, substituted or unsubstituted alkylthiol, substituted or unsubstituted alkoxy and substituted or unsubstituted phenyl. The compounds can inhibit pathogenic bacteria of botrytis cinerea, rice sheath blight disease, rice blast, corn northern leaf blight and wheat root rot, fusarium graminearum, phytophthora capsici, and other pathogenic bacteria, and can be used for control of diseases caused by the pathogenic bacteria. In addition, the compounds can inhibit growth of common monocotyledonous weeds and dicotyledonous weeds, such as amaranthus retroflexus, abutilon theophrasti Medicus, barnyard grass and digitaria sanguinalis (L.) Scop..