The invention discloses a high-crystallizability polyphenylene sulfide (PPS) self-lubricating resin composition and a preparation method thereof. The composition is composed of the following components in parts by mass: 85-100 parts of PPS and 1-15 parts of polytetrafluoroethylene. The preparation method comprises the following steps: premixing the PPS (of which the melt-flow rate is 150-800 g/10min) applicable to engineering plastics with the polytetrafluoroethylene powder of which the melting point is 295-315 DEG C in a stirrer, and performing melt mixing and granulation in a double screw extruder to prepare the composition. Compared with the existing PPS resin composition and composite material, the crystallization temperature of the melt after the start of cooling can be enhanced by 10 DEG C or above, and the composition disclosed by the invention can be crystallized quickly or by a room-temperature mold in the injection molding process, thereby being beneficial to enhancing the injection molding efficiency and lowering the processing energy consumption. The product has equivalent mechanical strength to a PPS resin, the friction factor can be lowered to 60% or below of the PPS resin, and the wear rate can be lowered to 10% of the PPS.