The invention discloses a type of chiral quinoline derivatives and particularly relates to optically-active chiral quinoline derivatives as indicated in the formula I and a preparation method thereof. The compounds can take tri(dibenzyl acetone) palladium chloroform admixture and P-S ligand as catalysts and 4-enyl benzene and oxazone and diazo compounds as starting raw materials, and are prepared by rearranging wolff and subsequent decarboxylation (4+2) cyclic reaction in visible light conditions. When P-S is the compound as indicated in the formula IV, the different substitutive chiral quinoline derivatives as indicated in the formula I can be synthesized efficiently with high enantioselectivity.