The invention relates to the radioactive source positioning field, and especially relates to a radioactive source positioning method and system. Multiple radioactive source detectors in different relative positions are adopted to carry out more than two times of detection on radioactive sources, and comparison is conducted on the basis of different detection results, so false positions during detection of the radioactive sources are removed. The radioactive source positioning method and system are simple in realization way, low in calculation complexity, and high in calculation precision.