The invention discloses a catalyst (Mx-My/Geo or Mx-My-Mz/Geo) prepared by supporting binary or ternary metals on a geopolymer (Geo), a preparation method thereof and application in a chemical heat pump. Multiple metals (copper, nickel, gold, ruthenium and the like) are supported on the surface of the special geopolymer to prepare the high-performance catalyst. The catalyst has the excellent conversion rate and selectivity for isopropanol dehydrogenation in the chemical heat pump and meets the requirements of industrial production.