The present invention discloses a vehicle-mounted oxygen generation apparatus, which comprises a central controller, an oxygen outlet device, a gas exchange device and an oxygen generation main machine, wherein the power supply of the oxygen generation main machine is taken from a vehicle storage battery power supply, the central controller performs information interaction through radio frequencysignals, and can control the starting, the stopping and the timing of the oxygen generation main machine through the radio frequency signals, the oxygen outlet of the oxygen outlet device is providedwith a mechanical valve, the oxygen generation main machine is connected to the oxygen outlet device through pipelines, the central controller controls the normal operations of the oxygen outlet device and the oxygen generation main machine, the power supply of the central controller is taken from a vehicle-mounted cigarette lighter interface. According to the present invention, the oxygen is prepared by using the outside-vehicle air as the raw material, and the waste gas is discharged out of the vehicle so as to increase the oxygen content in the vehicle; the central controller and the oxygengeneration main machine are separately arranged, such that the driver can easily control the oxygen generation main machine in the wheel house; and with the application of the mechanical valve to control the oxygen outlet, the mode is humanized, the point-to-point oxygen suction and the diffuse oxygen supply are provided, and the requirements of single people or multiple people on oxygen can be met.