The present invention discloses an active distribution network operation planning optimization method taking regard of electricity price response at a demand side. The method comprises: setting basicparameters of a particle swarm optimization, and performing initialization of an active distribution network operation plan corresponding to each particle; calculating a load variable amount and a netload of each node according to a demand side electricity price response formula; performing electric power system trend calculation, obtaining an active power requiring purchasing from a major network of each head-end node at each moment, and performing load cutting or electricity discarding according to a power off-limit condition; and calculating total operation cost of the active distributionnetwork, and obtaining an optimal operation plan and the minimum operation cost of the active distribution network through iteration of the particle swarm optimization. The active distribution networkoperation planning optimization method taking regard of electricity price response at a demand side considers cooperation regulation of a supply side and a demand side to commonly bring storage battery energy storage and electricity price responses at the demand side into the active distribution network operation plan optimization and fully develop peak cutting and valley filling capability of two sides of a 'source charge' so that receiving of an intermittent power supply is improved, a operation cost of a power distribution network is reduced and the active distribution network operation planning optimization method taking regard of electricity price response at a demand side can be applied to various occasions for distribution network operation optimization.