The invention relates to the technical field of anti-collision, in particular to a highway anti-collision guardrail. The highway anti-collision guardrail comprises a fixing device, inner buffering devices, outer buffering devices and rotating devices; the rotating devices each are of a concentric circle structure from inside to outside and are all arranged on the outer sides of vertical columns; the outer buffering devices are buffering cushions, when a vehicle collides with the highway anti-collision guardrail, collision kinetic energy can be reduced through air in hole layers of the buffering cushions and buffering layers of the buffering cushions, so that the collision process is prolonged, and force is dispersed; meanwhile the rotating devices further can rotate around the axial centerlines through bead layers when the vehicle is collided, accordingly collision force brought by objects such as the vehicle is guided to be deviated from the guardrail so as to better save a driver life; and in addition, light-emitting material layers arranged in reinforcing bands can emit light continuously for 1 h after being irradiated by various visible light, and thus the reflective warning effect is better on rainy days and foggy days, at night and in other situations that light rays are poor. The method is simple and easy to operate, waste plastic or waste rubber is fully utilized, materials are saved, and mounting is convenient.