The invention discloses a hollow B-ZSM-5 molecular sieve, and a preparation method and applications thereof. The hollow B-ZSM-5 molecular sieve is prepared from a molecular sieve crystal of a core-shell structure via alkali dissolution silicon removing; according to the molecular sieve crystal of a core-shell structure, powdery or structured MFI type silicon aluminium molecular sieve crystal seedis taken as the core, B-ZSM-5 molecular sieve is taken as the shell. The structured hollow B-ZSM-5 molecular sieve possesses the excellent diffusion performance of multistage pore molecular sieves, and the common advantages of structure catalysts; the structure is stable; the permeability is high; and the heat conduction performance is excellent. The hollow B-ZSM-5 molecular sieve is adopted in production of propylene from methanol via catalytic reaction, the single pass life is prolonged by about 85% when the weight hourly space velocity is 10h<-1>, and methanol conversion rate is larger than90%.