The invention discloses a heterogeneous material cutting device which comprises an upper frame and a lower frame. A lower screw is mounted on the lower frame, a lower knife holder is spirally mountedon the lower screw, an upper screw is mounted on the upper frame, an upper knife holder is spirally mounted on the upper screw, the upper screw and the lower screw are synchronously driven by a screwdriving motor, a plastic cutting knife is mounted on the upper knife holder, a glass cutting wheel is mounted on the lower knife holder, a plate carrying table is arranged above the lower frame, a notch is formed in the upper surface of the plate carrying table, the glass cutting wheel feeds through the notch, and a plate pressing device is arranged above the plate carrying table. According to thecutting device, damage to a bonding layer is reduced as far as possible by the aid of a pressing mechanism and a horizontal and uniform cutting movement mode, cutting pressure and cutting speed are controlled, cross section flatness after cutting of glass and high-molecular materials bound on the glass is improved, the cutting efficiency of the glass, the bonding layer and the high-molecular materials bound on the glass and the bonding layer is greatly improved in an automatic cutting manner, and potential safety hazards caused by manual cutting are reduced as far as possible.