The invention relates to a 3D printing huckle-bone prosthesis, and belongs to the technical field of medical science. The 3D printing huckle-bone prosthesis includes a huckle-bone head, a huckle-boneneck and a huckle-bone body which are connected integrally. The huckle-bone head, the huckle-bone neck and the huckle-bone body are made from Co-Cr-Mo alloy and formed through 3D-printing integrated molding; the huckle-bone head includes a forward huckle-bone articular surface, and the axis of the huckle-bone neck has an inward inclination angle of 15-20 degrees; the huckle-bone body includes a trochlea tali articular surface on the upper portion, an anterior calcanean articular surface on the lower portion, a middle calcanean articular surface, a posterior calcanean articular surface, a facies malleolaris medialis on the inner side, and a lateral malleolus articular surface on the outer side. The huckle-bone prosthesis is printed through the 3D printing technology, the huckle-bone head, the huckle-bone neck and the huckle-bone body are subjected to 3D-printing integrated molding, the service life is long, and after the huckle-bone prosthesis is implanted in the body of a patient, no parts need to be replaced; the 3D printing huckle-bone prosthesis is made from Co-Cr-Mo alloy, and the Co-Cr-Mo alloy and the human body do not have immunological rejection. The 3D printing huckle-boneprosthesis is designed through combination of big data statistics and the biomechanics, and the joint function of patients is retained to the greatest extent.