The invention relates to the technical field of heterogeneous catalysis, and in particular discloses a preparation method of a nickel granule embedded ordered mesoporous carbon catalyst and application. The preparation method of the nickel granule embedded ordered mesoporous carbon catalyst is characterized by comprising the following steps: soaking a nickel salt solution into a template agent, drying, and grinding to obtain powder; soaking the obtained powder with an organic matter solution as a carbon source, drying, and grinding; performing high-temperature roasting on the powder; treatingthe roasted product by a temperature agent removal agent, washing, drying, and grinding, thereby obtaining a product. The preparation method disclosed by the invention is simple, nickel granules in the obtained catalyst are not easily accumulated or grown, furthermore the catalyst is relatively good in activity and stability, the yield of a target yield can be up to 90% or greater, and the catalyst can be repeatedly used for more than ten times.