The invention discloses a method for constructing a dihydrobenzofuran skeleton compound by oxidative coupling of two C-H bonds. According to the method, an intramolecular oxidative coupling reaction of carbon-hydrogen bonds is carried out on a carbon hydrogen bond C(sp<2>)-H at the ortho-position of carboxyl on an aromatic ring in an alkoxy substituted benzoic acid derivative and a carbon-hydrogenbond C(sp<3>) on an alkoxy group for constructing a carbon-carbon bond, and then the dihydrobenzofuran skeleton compound is obtained. The method provided by the invention has an important applicationvalue.