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发明公开
CN107987138A Gal4温敏型突变体、重组表达载体、温度调控系统及其应用 有权

Gal4温敏型突变体、重组表达载体、温度调控系统及其应用
摘要：
本发明提供Gal4温敏型突变体，及利用其该突变体在酿酒酵母中构建温度调控系统及其应用。利用Gal4温敏型突变体构建的温度调控操作简单，无需添加诱导剂/抑制剂，实现对代谢流的精细调控。有利于其它对细胞毒性大的物质的生产。
摘要（英）：

The invention provides a Gal4 thermo-sensitive mutant, and a temperature regulation system constructed in saccharomyces cerevisiae by utilizing the mutant and application thereof. The temperature regulation system constructed by utilizing the Gal4 thermo-sensitive mutant is simple in operation, does not need to be added with an inducer/inhibitor, and can realize fine control of metabolic flux. Production of other substances with high toxicity to cells is promoted.

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