The invention discloses an antibacterial, hydrogen-rich and low-sugar healthcare drink with effects of strengthening heart protecting liver as well as a preparation method of the healthcare drink. Thehealthcare drink is prepared from raw materials by weight as follows: 0.5-0.8 g of potato peel residue flavones, 0.2-0.5 g of corn stigma phenolic acid, 0.5-2.0 g of corn cob xylooligosaccharide, 0.1-0.5 g of a dandelion root water-containing diethylether, 0.05-0.1 g of cordyceps sinensis active peptide and 0.05-0.1 g of a saffron crocus ethanol extract. The raw materials are mixed and prepared into natural drink pulp with 100 mL of purified water, 0.2-0.4 g of crosslinked potato starch is added, a natural antibacterial starch milk solution is prepared, the pulp solution obtained after vibrating mixing is treated with a low-speed homogenization method, a homogenate is obtained and sufficiently mixed with 0.50-0.60 mL of hydrogen by a venturi structure of a hydraulic jet pump, and the healthcare drink is prepared, and no artificially synthesized additives such as preservatives, aroma enhancers and thickeners are added to the product. The prepared functional healthcare drink is naturaland antibacterial, has outstanding functions and is suitable for the public, particularly groups with hyperglycemia, heart disease and poor livers.