The invention relates to a high-temperature protection system and method for a vehicle. The method includes the following steps that S1, an in-vehicle temperature and an outer temperature are obtainedthrough a temperature sensor, and if the in-vehicle temperature is higher than a first temperature and is further higher than the outer temperature by a second temperature, S2 is executed; S2, a motor control module operates a window control motor to roll down a window by a preset distance, the preset distance is 4-30mm, and then S3 is executed; S3, the in-vehicle temperature and the outer temperature are obtained through the temperature sensor, and if the in-vehicle temperature is lower than or equal to the first temperature, S4 is executed; and S4, the motor control module operates the window control motor to roll up the window until the window is closed. The high-temperature protection system and method for the vehicle have the advantages of being simple and reliable, convenient to maintain and the like. Moreover, high-temperature air in the vehicle can be exhausted smoothly when the vehicle is stopped, and various poor effects caused by the excessively-high in-vehicle temperatureare avoided.