The invention discloses a method for preparing a reproducible porous titanium-based composite bone material by 3D powder printing and belongs to the field of preparation of titanium-based composite materials. The method comprises carrying out mechanical mixing on mixed nanometer powder comprising 95.5% by mass of Ti, 1.6% by mass of Zn, 2.5% by mass of Mg and 0.4% by mass of Ag through mechanicalball milling for 24h, drying the uniform mixture at 80 DEG C for 1h to obtain a metal powder base, constructing a 3D printing model, carrying out printing through a maltodextrin-based liquid adhesive,after cladding, standing a 3D cladded member in a special hot atmosphere provided by incandescent lamp heating for 60min, blowing to separate the unmelted powder from a scaffold through high pressureair flows, after unmelted powder removal, putting the scaffold into an argon gas protection electron furnace, and carrying out sintering. The porous design of the implant improves the adhesion and proliferation of cells and production of new blood vessels and realizes bone regeneration. The titanium-based composite material improves the corrosion resistance, wear resistance and antibacterial andanti-virus properties of the titanium alloy.