The invention relates to a high-safety intelligent processing system for a cylindrical winding of a power grid transformer. The high-safety intelligent processing system comprises a bottom plate, wherein two installation lugs are symmetrically arranged on an upper end surface of the bottom plate, an insulation cylinder is arranged between the two installation lugs by a bearing, a winding motor isarranged at a front end of the insulation cylinder by a coupler, a bottom end of the winding motor is arranged on a vertical plate by a motor seat, the vertical plate is welded on the bottom plate, the insulation cylinder is driven to rotate on the two installation lugs by the winding motor, a mobile tension device is arranged at a left end of the bottom plate, a wire strip penetrates through a V-shape structure on the mobile tension device, the mobile tension device can be used for adjusting a position in real time according to a winding position of the wire strip, the tension position is notneeded to be adjusted by manual, an initial end of the wire strip is wound around the insulation cylinder, and the wire strip is wound around an outer wall of the insulation cylinder for a pluralityof times to form the cylindrical winding. By the high-safety intelligent processing system, the full-automatic tension winding function of the cylindrical winding can be achieved, and the high-performance transformer comprising the cylindrical winding also can be fabricated.